PAUSCH LAB

GENOME EDITOR
DISCOVERY & DEVELOPMENT

Viruses and prokaryotes are a biotechnological treasure trove of evolution. Billions of years of prokaryote-virus conflict and co-evolution have generated a fascinating diversity of nucleic acid interacting and modifying enzymes, which can be used to manipulate nucleic acids in virtually any context. Our research focuses on the discovery of new, and enhancement of existing nucleic acid modifying tools such as CRISPR. We utilize a range of microbiological techniques, biochemical approaches and structural biology to identify, characterize and develop new enzymes for biotechnology, agriculture and medicine.